Drug interactions
Ganciclovir + Hydrochlorothiazide-telmisartan
Severity: Minor
Ganciclovir and Hydrochlorothiazide-telmisartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs depend on renal elimination including tubular secretion, so hydrochlorothiazide may modestly raise ganciclovir exposure. Volume depletion from the diuretic may also reduce renal function and increase ganciclovir toxicity such as myelosuppression.
What this interaction means in plain words
Ganciclovir and Hydrochlorothiazide-telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ganciclovir belongs to Anti Virals; Hydrochlorothiazide-telmisartan belongs to Cardiovascular.
Why it happens
Competition for renal tubular secretion and diuretic-related reduction in renal clearance.
What to do
Monitor renal function and blood counts, and adjust ganciclovir dose to creatinine clearance.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Other interactions of Ganciclovir
Frequently asked questions
Can I take Ganciclovir with Hydrochlorothiazide-telmisartan?
MediHelp rates the interaction as minor. Ganciclovir and Hydrochlorothiazide-telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs depend on renal elimination including tubular secretion, so hydrochlorothiazide may modestly raise ganciclovir exposure. Volume depletion from the diuretic may also reduce renal function and increase ganciclovir toxicity such as myelosuppression.
How serious is the interaction between Ganciclovir and Hydrochlorothiazide-telmisartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and blood counts, and adjust ganciclovir dose to creatinine clearance.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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