Drug interactions
Garlic + Reishi
Severity: Moderate
Garlic and Reishi: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reishi mushroom has been reported to inhibit platelet aggregation, and garlic has similar effects. Combined use may increase bleeding tendency, especially with other antithrombotics.
What this interaction means in plain words
Garlic and Reishi can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive inhibition of platelet aggregation by constituents of both products.
What to do
Avoid combining in patients on anticoagulants or antiplatelets and stop before surgery. Monitor for bleeding.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Garlic
- Garlic + Saquinavir Major
- Aceclofenac + Garlic Moderate
- Acemetacin + Garlic Moderate
- Aescin + Garlic Moderate
- Alteplase + Garlic Moderate
- Argatroban + Garlic Moderate
Frequently asked questions
Can I take Garlic with Reishi?
MediHelp rates the interaction as moderate. Garlic and Reishi can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Reishi mushroom has been reported to inhibit platelet aggregation, and garlic has similar effects. Combined use may increase bleeding tendency, especially with other antithrombotics.
How serious is the interaction between Garlic and Reishi?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining in patients on anticoagulants or antiplatelets and stop before surgery. Monitor for bleeding.
What other medicines interact with Garlic?
MediHelp also lists interactions of Garlic with, for example, Saquinavir, Aceclofenac, Acemetacin. The full list is on the Garlic page.
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