Drug interactions
Ginkgo biloba + Meclofenamic acid
Severity: Moderate
Ginkgo biloba and Meclofenamic acid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo inhibits platelet-activating factor and has been linked to case reports of bleeding. Combined with an NSAID that impairs platelet function and irritates the gut, the risk of bleeding may rise.
What this interaction means in plain words
Ginkgo biloba and Meclofenamic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antiplatelet effects: ginkgolide antagonism of platelet-activating factor plus NSAID COX-1 inhibition.
What to do
Ask about ginkgo use and discourage the combination where possible. Monitor for bleeding and stop ginkgo before surgery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Meclofenamic acid
- Ketorolac intranasal + Meclofenamic acid Contraindicated
- Ketorolac + Meclofenamic acid Contraindicated
- Aceclofenac + Meclofenamic acid Major
- Acemetacin + Meclofenamic acid Major
- Alteplase + Meclofenamic acid Major
- Amiloride + Meclofenamic acid Major
Frequently asked questions
Can I take Ginkgo biloba with Meclofenamic acid?
MediHelp rates the interaction as moderate. Ginkgo biloba and Meclofenamic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo inhibits platelet-activating factor and has been linked to case reports of bleeding. Combined with an NSAID that impairs platelet function and irritates the gut, the risk of bleeding may rise.
How serious is the interaction between Ginkgo biloba and Meclofenamic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about ginkgo use and discourage the combination where possible. Monitor for bleeding and stop ginkgo before surgery.
What other medicines interact with Meclofenamic acid?
MediHelp also lists interactions of Meclofenamic acid with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meclofenamic acid page.
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