Drug interactions
Glatiramer + Tocilizumab
Severity: Minor
Glatiramer and Tocilizumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glatiramer is an immunomodulator rather than a broadly immunosuppressive drug, and no meaningful additive infection risk is established with tocilizumab. The legacy concern is largely theoretical and the two are not known to interact.
What this interaction means in plain words
Glatiramer and Tocilizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Glatiramer belongs to Central Nervous System; Tocilizumab belongs to Musculoskeletal.
Why it happens
No established mechanism; only theoretical additive immune modulation.
What to do
No change is needed. Monitor for infection as is routine with tocilizumab.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tocilizumab
- Bcg vaccine live + Tocilizumab Contraindicated
- Measles mumps and rubella vaccine live + Tocilizumab Contraindicated
- Measles mumps rubella and varicella vaccine live + Tocilizumab Contraindicated
- Measles vaccine + Tocilizumab Contraindicated
- Rubella vaccine + Tocilizumab Contraindicated
- Smallpox vaccine live + Tocilizumab Contraindicated
Other interactions of Glatiramer
- Anakinra + Glatiramer Minor
- Anti-thymocyte + Glatiramer Minor
- Basiliximab + Glatiramer Minor
- Denosumab + Glatiramer Minor
- Echinacea + Glatiramer Minor
- Etanercept + Glatiramer Minor
Frequently asked questions
Can I take Glatiramer with Tocilizumab?
MediHelp rates the interaction as minor. Glatiramer and Tocilizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glatiramer is an immunomodulator rather than a broadly immunosuppressive drug, and no meaningful additive infection risk is established with tocilizumab. The legacy concern is largely theoretical and the two are not known to interact.
How serious is the interaction between Glatiramer and Tocilizumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is needed. Monitor for infection as is routine with tocilizumab.
What other medicines interact with Tocilizumab?
MediHelp also lists interactions of Tocilizumab with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Tocilizumab page.
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