Drug interactions
Gliclazide + Sage
Severity: Minor
Gliclazide and Sage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sage has been reported to have blood glucose-lowering activity in small studies. Used together with gliclazide, it might add to the hypoglycemic effect, although evidence is limited and product content varies.
What this interaction means in plain words
Gliclazide and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive glucose-lowering activity of sage constituents; mechanism not well established.
What to do
Advise patients to report use of sage supplements and monitor blood glucose for hypoglycemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Gliclazide
Frequently asked questions
Can I take Gliclazide with Sage?
MediHelp rates the interaction as minor. Gliclazide and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sage has been reported to have blood glucose-lowering activity in small studies. Used together with gliclazide, it might add to the hypoglycemic effect, although evidence is limited and product content varies.
How serious is the interaction between Gliclazide and Sage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report use of sage supplements and monitor blood glucose for hypoglycemia.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
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