Drug interactions
Gliclazide + Selegiline transdermal
Severity: Minor
Gliclazide and Selegiline transdermal: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
MAO inhibitors have been associated with enhanced hypoglycemia in patients taking antidiabetic drugs. At transdermal antidepressant doses the effect is uncertain and probably small.
What this interaction means in plain words
Gliclazide and Selegiline transdermal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Not established; MAO inhibition may influence insulin secretion and glucose regulation.
What to do
Monitor blood glucose when starting or stopping selegiline and adjust gliclazide if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Gliclazide
Frequently asked questions
Can I take Gliclazide with Selegiline transdermal?
MediHelp rates the interaction as minor. Gliclazide and Selegiline transdermal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. MAO inhibitors have been associated with enhanced hypoglycemia in patients taking antidiabetic drugs. At transdermal antidepressant doses the effect is uncertain and probably small.
How serious is the interaction between Gliclazide and Selegiline transdermal?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping selegiline and adjust gliclazide if hypoglycemia occurs.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
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