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Drug interactions

Gliclazide + Shark cartilage

Severity: Minor

Gliclazide and Shark cartilage: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Shark cartilage has been suggested to affect blood glucose and may add to the effect of antidiabetic drugs, but this is largely theoretical. Clinical data are very limited.

What this interaction means in plain words

Gliclazide and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical additive glucose lowering; no mechanism is established.

What to do

Advise patients to report supplement use and monitor blood glucose if started or stopped.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Gliclazide with Shark cartilage?

MediHelp rates the interaction as minor. Gliclazide and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shark cartilage has been suggested to affect blood glucose and may add to the effect of antidiabetic drugs, but this is largely theoretical. Clinical data are very limited.

How serious is the interaction between Gliclazide and Shark cartilage?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report supplement use and monitor blood glucose if started or stopped.

What other medicines interact with Gliclazide?

MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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