Drug interactions
Gliclazide + Triamcinolone acetonide injectable
Severity: Moderate
Gliclazide and Triamcinolone acetonide injectable: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroids raise blood glucose and can offset the effect of gliclazide. Injected triamcinolone can cause hyperglycemia lasting days to weeks.
What this interaction means in plain words
Gliclazide and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Glucocorticoids increase hepatic gluconeogenesis and peripheral insulin resistance, opposing sulfonylurea action.
What to do
Monitor glucose more often for several weeks after injection and increase antidiabetic therapy if needed; watch for hypoglycemia as the steroid effect wanes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Gliclazide
Frequently asked questions
Can I take Gliclazide with Triamcinolone acetonide injectable?
MediHelp rates the interaction as moderate. Gliclazide and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids raise blood glucose and can offset the effect of gliclazide. Injected triamcinolone can cause hyperglycemia lasting days to weeks.
How serious is the interaction between Gliclazide and Triamcinolone acetonide injectable?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose more often for several weeks after injection and increase antidiabetic therapy if needed; watch for hypoglycemia as the steroid effect wanes.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
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