Drug interactions
Gliclazide + Vanadium
Severity: Minor
Gliclazide and Vanadium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vanadium compounds have insulin-mimetic properties and can lower blood glucose. With gliclazide, an additive effect and hypoglycemia are theoretically possible, although clinical evidence is limited.
What this interaction means in plain words
Gliclazide and Vanadium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Insulin-mimetic activity of vanadium adds to sulfonylurea-stimulated insulin secretion.
What to do
Monitor blood glucose in patients taking vanadium supplements with gliclazide and reduce the sulfonylurea dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Gliclazide
Frequently asked questions
Can I take Gliclazide with Vanadium?
MediHelp rates the interaction as minor. Gliclazide and Vanadium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vanadium compounds have insulin-mimetic properties and can lower blood glucose. With gliclazide, an additive effect and hypoglycemia are theoretically possible, although clinical evidence is limited.
How serious is the interaction between Gliclazide and Vanadium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose in patients taking vanadium supplements with gliclazide and reduce the sulfonylurea dose if hypoglycemia occurs.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
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