Drug interactions
Glipizide-metformin + Phendimetrazine
Severity: Minor
Glipizide-metformin and Phendimetrazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sympathomimetic anorectics can alter glucose requirements. Weight loss and reduced intake may increase hypoglycemia risk with glipizide, while sympathomimetic effects can transiently raise glucose.
What this interaction means in plain words
Glipizide-metformin and Phendimetrazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Sympathomimetic effects and reduced caloric intake alter glucose control.
What to do
Monitor glucose when starting or stopping phendimetrazine and reduce glipizide if hypoglycemia develops with weight loss.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Glipizide-metformin and Phendimetrazine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Glipizide-metformin
Frequently asked questions
Can I take Glipizide-metformin with Phendimetrazine?
MediHelp rates the interaction as minor. Glipizide-metformin and Phendimetrazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sympathomimetic anorectics can alter glucose requirements. Weight loss and reduced intake may increase hypoglycemia risk with glipizide, while sympathomimetic effects can transiently raise glucose.
How serious is the interaction between Glipizide-metformin and Phendimetrazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose when starting or stopping phendimetrazine and reduce glipizide if hypoglycemia develops with weight loss.
What other medicines interact with Glipizide-metformin?
MediHelp also lists interactions of Glipizide-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Glipizide-metformin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
