Drug interactions
Glipizide-metformin + Tongkat ali
Severity: Minor
Glipizide-metformin and Tongkat ali: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tongkat ali has been reported to have glucose-lowering properties in animal and limited human data. With glipizide and metformin it could increase the risk of hypoglycemia.
What this interaction means in plain words
Glipizide-metformin and Tongkat ali have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive hypoglycemic effect; mechanism is not well characterized.
What to do
Advise patients to monitor blood glucose and recognize hypoglycemia symptoms if they use tongkat ali.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glipizide-metformin
Frequently asked questions
Can I take Glipizide-metformin with Tongkat ali?
MediHelp rates the interaction as minor. Glipizide-metformin and Tongkat ali have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tongkat ali has been reported to have glucose-lowering properties in animal and limited human data. With glipizide and metformin it could increase the risk of hypoglycemia.
How serious is the interaction between Glipizide-metformin and Tongkat ali?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to monitor blood glucose and recognize hypoglycemia symptoms if they use tongkat ali.
What other medicines interact with Glipizide-metformin?
MediHelp also lists interactions of Glipizide-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Glipizide-metformin page.
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