Drug interactions
Glucagon intranasal + Scopolamine
Severity: Moderate
Glucagon intranasal and Scopolamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon inhibits gastrointestinal motility, and anticholinergics such as scopolamine have the same effect. Together they can increase gastrointestinal adverse effects such as constipation, ileus or abdominal distension.
What this interaction means in plain words
Glucagon intranasal and Scopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive inhibition of gastrointestinal motility via pharmacodynamic synergism.
What to do
Monitor for reduced bowel activity, abdominal distension and pain. Consider an alternative to scopolamine if gastrointestinal symptoms develop, especially in patients prone to ileus.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Scopolamine
Frequently asked questions
Can I take Glucagon intranasal with Scopolamine?
MediHelp rates the interaction as moderate. Glucagon intranasal and Scopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glucagon inhibits gastrointestinal motility, and anticholinergics such as scopolamine have the same effect. Together they can increase gastrointestinal adverse effects such as constipation, ileus or abdominal distension.
How serious is the interaction between Glucagon intranasal and Scopolamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced bowel activity, abdominal distension and pain. Consider an alternative to scopolamine if gastrointestinal symptoms develop, especially in patients prone to ileus.
What other medicines interact with Scopolamine?
MediHelp also lists interactions of Scopolamine with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Scopolamine page.
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