Drug interactions
Glyburide-metformin + Shark cartilage
Severity: Minor
Glyburide-metformin and Shark cartilage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shark cartilage has been theorized to lower blood glucose, which could add to the effect of glyburide and metformin. Evidence is minimal.
What this interaction means in plain words
Glyburide-metformin and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive glucose-lowering effect; mechanism not established.
What to do
Monitor blood glucose if the patient uses shark cartilage supplements.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glyburide-metformin
Frequently asked questions
Can I take Glyburide-metformin with Shark cartilage?
MediHelp rates the interaction as minor. Glyburide-metformin and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shark cartilage has been theorized to lower blood glucose, which could add to the effect of glyburide and metformin. Evidence is minimal.
How serious is the interaction between Glyburide-metformin and Shark cartilage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if the patient uses shark cartilage supplements.
What other medicines interact with Glyburide-metformin?
MediHelp also lists interactions of Glyburide-metformin with, for example, Bosentan, Cholic acid, Clarithromycin. The full list is on the Glyburide-metformin page.
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