Drug interactions
Gold sodium thiomalate + Moexipril
Severity: Moderate
Gold sodium thiomalate and Moexipril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Injectable gold has been associated with nitritoid reactions such as flushing, nausea, vomiting and hypotension, and these appear more frequent in patients taking ACE inhibitors. The reactions are usually transient but can be distressing.
What this interaction means in plain words
Gold sodium thiomalate and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Not clearly established; likely vasodilatory effects of gold potentiated by ACE inhibition and raised bradykinin.
What to do
Observe patients after each gold injection and consider an alternative to the ACE inhibitor if reactions recur. Stopping or switching therapy is usually sufficient.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Frequently asked questions
Can I take Gold sodium thiomalate with Moexipril?
MediHelp rates the interaction as moderate. Gold sodium thiomalate and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Injectable gold has been associated with nitritoid reactions such as flushing, nausea, vomiting and hypotension, and these appear more frequent in patients taking ACE inhibitors. The reactions are usually transient but can be distressing.
How serious is the interaction between Gold sodium thiomalate and Moexipril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Observe patients after each gold injection and consider an alternative to the ACE inhibitor if reactions recur. Stopping or switching therapy is usually sufficient.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
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