Drug interactions
Green tea + Isocarboxazid
Severity: Moderate
Green tea and Isocarboxazid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Green tea contains caffeine, a stimulant that can add to the pressor effects of MAO inhibition. Large amounts may contribute to hypertension, palpitations or arrhythmia.
What this interaction means in plain words
Green tea and Isocarboxazid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Green tea belongs to Gastrointestinal Tract; Isocarboxazid belongs to Central Nervous System.
Why it happens
Caffeine's sympathomimetic effect combined with MAO inhibition, which impairs breakdown of catecholamines and tyramine.
What to do
Limit green tea and other caffeine intake and avoid concentrated extracts or supplements. Monitor blood pressure and heart rate, and counsel the patient about palpitations or severe headache.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Isocarboxazid
- 5-HTP + Isocarboxazid Contraindicated
- Amitriptyline + Isocarboxazid Contraindicated
- Amobarbital + Isocarboxazid Contraindicated
- Amoxapine + Isocarboxazid Contraindicated
- Apraclonidine + Isocarboxazid Contraindicated
- Atomoxetine + Isocarboxazid Contraindicated
Other interactions of Green tea
- Adenosine + Green tea Moderate
- Benzphetamine + Green tea Moderate
- Bortezomib + Green tea Moderate
- Dextroamphetamine + Green tea Moderate
- Diethylpropion + Green tea Moderate
- Ephedrine + Green tea Moderate
Frequently asked questions
Can I take Green tea with Isocarboxazid?
MediHelp rates the interaction as moderate. Green tea and Isocarboxazid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Green tea contains caffeine, a stimulant that can add to the pressor effects of MAO inhibition. Large amounts may contribute to hypertension, palpitations or arrhythmia.
How serious is the interaction between Green tea and Isocarboxazid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit green tea and other caffeine intake and avoid concentrated extracts or supplements. Monitor blood pressure and heart rate, and counsel the patient about palpitations or severe headache.
What other medicines interact with Isocarboxazid?
MediHelp also lists interactions of Isocarboxazid with, for example, 5-HTP, Amitriptyline, Amobarbital. The full list is on the Isocarboxazid page.
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