Drug interactions
Griseofulvin + Metformin-repaglinide
Severity: Minor
Griseofulvin and Metformin-repaglinide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin is a CYP3A4 inducer and may lower repaglinide concentrations, potentially reducing glycemic control.
What this interaction means in plain words
Griseofulvin and Metformin-repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Griseofulvin belongs to Anti Fungals; Metformin-repaglinide belongs to Endocrine.
Why it happens
Induction of CYP3A4 increasing repaglinide metabolism.
What to do
Monitor blood glucose during griseofulvin therapy and increase the repaglinide dose if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-repaglinide
Other interactions of Griseofulvin
Frequently asked questions
Can I take Griseofulvin with Metformin-repaglinide?
MediHelp rates the interaction as minor. Griseofulvin and Metformin-repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin is a CYP3A4 inducer and may lower repaglinide concentrations, potentially reducing glycemic control.
How serious is the interaction between Griseofulvin and Metformin-repaglinide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during griseofulvin therapy and increase the repaglinide dose if control worsens.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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