Drug interactions
Griseofulvin + Sulfasalazine
Severity: Minor
Griseofulvin and Sulfasalazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
A reduction in sulfasalazine levels has been suggested with griseofulvin, but there is no solid clinical evidence of reduced efficacy.
What this interaction means in plain words
Griseofulvin and Sulfasalazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mechanism is not established.
What to do
Monitor disease control in inflammatory bowel disease or arthritis. No dose change is needed without loss of response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Griseofulvin
Frequently asked questions
Can I take Griseofulvin with Sulfasalazine?
MediHelp rates the interaction as minor. Griseofulvin and Sulfasalazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. A reduction in sulfasalazine levels has been suggested with griseofulvin, but there is no solid clinical evidence of reduced efficacy.
How serious is the interaction between Griseofulvin and Sulfasalazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor disease control in inflammatory bowel disease or arthritis. No dose change is needed without loss of response.
What other medicines interact with Griseofulvin?
MediHelp also lists interactions of Griseofulvin with, for example, Cyclosporine, Cyclosporin, Desogestrel-ethinyl estradiol. The full list is on the Griseofulvin page.
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