Drug interactions
Griseofulvin + Theophylline
Severity: Minor
Griseofulvin and Theophylline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin is a weak enzyme inducer and may lower theophylline concentrations in some patients, which could reduce asthma control. The evidence is limited and the effect is generally modest.
What this interaction means in plain words
Griseofulvin and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Griseofulvin belongs to Anti Fungals; Theophylline belongs to Respiratory.
Why it happens
Possible induction of hepatic cytochrome P450 enzymes involved in theophylline metabolism.
What to do
Monitor clinical response and theophylline levels when griseofulvin is started or stopped, and adjust the dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Theophylline
- Riociguat + Theophylline Contraindicated
- Adenosine + Theophylline Major
- Apalutamide + Theophylline Major
- Bupropion + Theophylline Major
- Carvedilol + Theophylline Major
- Cimetidine + Theophylline Major
Other interactions of Griseofulvin
Frequently asked questions
Can I take Griseofulvin with Theophylline?
MediHelp rates the interaction as minor. Griseofulvin and Theophylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin is a weak enzyme inducer and may lower theophylline concentrations in some patients, which could reduce asthma control. The evidence is limited and the effect is generally modest.
How serious is the interaction between Griseofulvin and Theophylline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response and theophylline levels when griseofulvin is started or stopped, and adjust the dose if needed.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
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