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Drug interactions

Henbane + Rocuronium

Severity: Minor

Henbane and Rocuronium: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Henbane contains hyoscyamine and scopolamine, which are antimuscarinic and do not significantly affect nicotinic neuromuscular blockade. Additive anticholinergic effects such as tachycardia or dry mouth are possible.

What this interaction means in plain words

Henbane and Rocuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Antimuscarinic alkaloids produce additive autonomic effects without a clear action on rocuronium's nicotinic blockade.

What to do

No dose change is needed; monitor heart rate and advise the patient to stop herbal henbane before elective surgery.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Henbane with Rocuronium?

MediHelp rates the interaction as minor. Henbane and Rocuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Henbane contains hyoscyamine and scopolamine, which are antimuscarinic and do not significantly affect nicotinic neuromuscular blockade. Additive anticholinergic effects such as tachycardia or dry mouth are possible.

How serious is the interaction between Henbane and Rocuronium?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; monitor heart rate and advise the patient to stop herbal henbane before elective surgery.

What other medicines interact with Rocuronium?

MediHelp also lists interactions of Rocuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Rocuronium page.

Full monographs, dosing and an interaction checker in the MediHelp app

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