Drug interactions
Heparin + Moexipril
Severity: Moderate
Heparin and Moexipril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Heparin can suppress aldosterone secretion and cause hyperkalemia. With an ACE inhibitor the risk of elevated potassium rises, especially in diabetes, renal impairment or prolonged use.
What this interaction means in plain words
Heparin and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Heparin belongs to Cardiovascular; Moexipril belongs to Cardiovascular.
Why it happens
Additive reduction in aldosterone effect: heparin inhibits adrenal aldosterone synthesis and ACE inhibition lowers angiotensin II.
What to do
Monitor serum potassium when heparin is continued beyond several days, particularly in high-risk patients. Treat hyperkalemia or reconsider therapy if it develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Other interactions of Heparin
- Defibrotide + Heparin Contraindicated
- Heparin + Ketorolac Contraindicated
- Heparin + Oritavancin Contraindicated
- Acemetacin + Heparin Major
- Acetylsalicylic acid + Heparin Major
- Alteplase + Heparin Major
Frequently asked questions
Can I take Heparin with Moexipril?
MediHelp rates the interaction as moderate. Heparin and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Heparin can suppress aldosterone secretion and cause hyperkalemia. With an ACE inhibitor the risk of elevated potassium rises, especially in diabetes, renal impairment or prolonged use.
How serious is the interaction between Heparin and Moexipril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium when heparin is continued beyond several days, particularly in high-risk patients. Treat hyperkalemia or reconsider therapy if it develops.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
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