Drug interactions
Hydrochlorothiazide-telmisartan + Insulin inhaled
Severity: Moderate
Hydrochlorothiazide-telmisartan and Insulin inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide can raise blood glucose and reduce the effect of insulin, while telmisartan may slightly increase insulin sensitivity. Glycemic control can therefore shift and insulin needs may change.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Insulin inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Thiazide-induced insulin resistance and hypokalemia oppose insulin action, whereas ARBs may enhance insulin sensitivity.
What to do
Monitor blood glucose when starting or changing the antihypertensive and adjust the insulin dose as needed. Maintain normal serum potassium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Insulin inhaled?
MediHelp rates the interaction as moderate. Hydrochlorothiazide-telmisartan and Insulin inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydrochlorothiazide can raise blood glucose and reduce the effect of insulin, while telmisartan may slightly increase insulin sensitivity. Glycemic control can therefore shift and insulin needs may change.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Insulin inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or changing the antihypertensive and adjust the insulin dose as needed. Maintain normal serum potassium.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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