Drug interactions
Hydrochlorothiazide-telmisartan + Juniper
Severity: Moderate
Hydrochlorothiazide-telmisartan and Juniper: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Juniper berry has diuretic properties and could add to the fluid and electrolyte losses caused by hydrochlorothiazide. Large amounts of juniper have also been linked to renal irritation, which is undesirable in a patient taking an ARB and a thiazide.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Juniper can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive diuretic effect; the herb's pharmacology is poorly standardized and the interaction is largely theoretical.
What to do
Discourage use of juniper products in patients on this combination. If used, monitor blood pressure, hydration status, serum electrolytes and renal function.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Juniper?
MediHelp rates the interaction as moderate. Hydrochlorothiazide-telmisartan and Juniper can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Juniper berry has diuretic properties and could add to the fluid and electrolyte losses caused by hydrochlorothiazide. Large amounts of juniper have also been linked to renal irritation, which is undesirable in a patient taking an ARB and a thiazide.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Juniper?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Discourage use of juniper products in patients on this combination. If used, monitor blood pressure, hydration status, serum electrolytes and renal function.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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