Drug interactions
Hydrochlorothiazide-telmisartan + Nafcillin
Severity: Minor
Hydrochlorothiazide-telmisartan and Nafcillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazides and penicillins are both eliminated by renal tubular secretion, so competition could modestly raise levels of either. Clinical impact is likely small, and nafcillin is eliminated largely through the liver.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Nafcillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible competition for renal tubular anionic secretion.
What to do
No routine adjustment is needed; monitor clinically for adverse effects during prolonged therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Hydrochlorothiazide-telmisartan and Nafcillin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Nafcillin?
MediHelp rates the interaction as minor. Hydrochlorothiazide-telmisartan and Nafcillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazides and penicillins are both eliminated by renal tubular secretion, so competition could modestly raise levels of either. Clinical impact is likely small, and nafcillin is eliminated largely through the liver.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Nafcillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; monitor clinically for adverse effects during prolonged therapy.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
