Drug interactions
Hydrochlorothiazide-telmisartan + Pindolol
Severity: Minor
Hydrochlorothiazide-telmisartan and Pindolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pindolol is a beta-blocker that adds to the blood pressure lowering of telmisartan and hydrochlorothiazide, which is often intended but can cause hypotension or bradycardia. Beta-blockers may also blunt the rise in heart rate that normally follows excessive vasodilation or volume loss. Beta-blockade can mask hypoglycemia symptoms, and thiazides can raise glucose.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive pharmacodynamic antihypertensive effects from beta-adrenergic blockade combined with angiotensin receptor blockade and diuresis.
What to do
Monitor blood pressure and heart rate when starting or adjusting either agent, and adjust doses if symptomatic hypotension or bradycardia occurs. Monitor glucose in diabetic patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Pindolol?
MediHelp rates the interaction as minor. Hydrochlorothiazide-telmisartan and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pindolol is a beta-blocker that adds to the blood pressure lowering of telmisartan and hydrochlorothiazide, which is often intended but can cause hypotension or bradycardia. Beta-blockers may also blunt the rise in heart rate that normally follows excessive vasodilation or volume loss. Beta-blockade can mask hypoglycemia symptoms, and thiazides can raise glucose.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Pindolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting either agent, and adjust doses if symptomatic hypotension or bradycardia occurs. Monitor glucose in diabetic patients.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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