Drug interactions
Hydrochlorothiazide-telmisartan + Shark cartilage
Severity: Minor
Hydrochlorothiazide-telmisartan and Shark cartilage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shark cartilage supplements contain calcium and have been associated with hypercalcemia, and thiazides reduce urinary calcium excretion. In combination, serum calcium could rise, though this is mainly theoretical.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive effect on serum calcium from calcium content of the supplement and reduced renal calcium excretion caused by the thiazide.
What to do
Check serum calcium if the supplement is taken regularly, and discourage its use if hypercalcemia symptoms develop.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Shark cartilage?
MediHelp rates the interaction as minor. Hydrochlorothiazide-telmisartan and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shark cartilage supplements contain calcium and have been associated with hypercalcemia, and thiazides reduce urinary calcium excretion. In combination, serum calcium could rise, though this is mainly theoretical.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Shark cartilage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum calcium if the supplement is taken regularly, and discourage its use if hypercalcemia symptoms develop.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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