Drug interactions
Hydrochlorothiazide-telmisartan + Shepherd's purse
Severity: Minor
Hydrochlorothiazide-telmisartan and Shepherd's purse: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shepherd's purse has been traditionally reported to affect blood pressure, and it could theoretically work against the antihypertensive action of telmisartan. Clinical evidence is lacking and the interaction is speculative.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic opposition to blood pressure control; mechanism not established.
What to do
Discourage use of shepherd's purse in patients with hypertension, or monitor blood pressure if it is taken.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Shepherd's purse?
MediHelp rates the interaction as minor. Hydrochlorothiazide-telmisartan and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shepherd's purse has been traditionally reported to affect blood pressure, and it could theoretically work against the antihypertensive action of telmisartan. Clinical evidence is lacking and the interaction is speculative.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Shepherd's purse?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Discourage use of shepherd's purse in patients with hypertension, or monitor blood pressure if it is taken.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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