Drug interactions
Hydrochlorothiazide-telmisartan + Temocillin
Severity: Minor
Hydrochlorothiazide-telmisartan and Temocillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Temocillin is excreted mainly by the kidney through filtration and tubular secretion, and thiazides may compete for tubular secretion, but clinically meaningful changes are not well documented. Volume depletion from the diuretic could modestly reduce renal clearance.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible competition for renal tubular secretion, not well established clinically.
What to do
No dose adjustment is generally needed; monitor renal function and hydration status.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Temocillin?
MediHelp rates the interaction as minor. Hydrochlorothiazide-telmisartan and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Temocillin is excreted mainly by the kidney through filtration and tubular secretion, and thiazides may compete for tubular secretion, but clinically meaningful changes are not well documented. Volume depletion from the diuretic could modestly reduce renal clearance.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Temocillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is generally needed; monitor renal function and hydration status.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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