Drug interactions
Hydrochlorothiazide-telmisartan + Ticarcillin
Severity: Moderate
Hydrochlorothiazide-telmisartan and Ticarcillin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ticarcillin is cleared by the kidney and carries a significant sodium load and hypokalemia risk. Combined with hydrochlorothiazide, potassium depletion may be additive, and volume depletion may reduce penicillin clearance.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Ticarcillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive renal potassium loss from thiazide and ticarcillin, with possible competition for tubular secretion.
What to do
Monitor serum potassium and renal function during ticarcillin therapy and replace potassium if low.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Ticarcillin?
MediHelp rates the interaction as moderate. Hydrochlorothiazide-telmisartan and Ticarcillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ticarcillin is cleared by the kidney and carries a significant sodium load and hypokalemia risk. Combined with hydrochlorothiazide, potassium depletion may be additive, and volume depletion may reduce penicillin clearance.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Ticarcillin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function during ticarcillin therapy and replace potassium if low.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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