Drug interactions
Hydrochlorothiazide-valsartan + Mometasone inhaled
Severity: Minor
Hydrochlorothiazide-valsartan and Mometasone inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids can cause potassium loss and may add to thiazide-induced hypokalemia. With inhaled mometasone systemic exposure is low, so the effect is usually small.
What this interaction means in plain words
Hydrochlorothiazide-valsartan and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mineralocorticoid-like potassium wasting from corticosteroids adds to thiazide kaliuresis, but only minimally with inhaled doses.
What to do
No action is usually needed; check potassium periodically if high doses or other potassium-lowering drugs are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-valsartan
- Aliskiren + Hydrochlorothiazide-valsartan Contraindicated
- Dofetilide + Hydrochlorothiazide-valsartan Contraindicated
- Hydrochlorothiazide-valsartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-valsartan Major
- Amifostine + Hydrochlorothiazide-valsartan Major
- Amiloride + Hydrochlorothiazide-valsartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-valsartan with Mometasone inhaled?
MediHelp rates the interaction as minor. Hydrochlorothiazide-valsartan and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids can cause potassium loss and may add to thiazide-induced hypokalemia. With inhaled mometasone systemic exposure is low, so the effect is usually small.
How serious is the interaction between Hydrochlorothiazide-valsartan and Mometasone inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is usually needed; check potassium periodically if high doses or other potassium-lowering drugs are used.
What other medicines interact with Hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-valsartan page.
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