Drug interactions
Hydroxyurea + Ixabepilone
Severity: Moderate
Hydroxyurea and Ixabepilone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs suppress bone marrow. The combination may produce more severe neutropenia and thrombocytopenia.
What this interaction means in plain words
Hydroxyurea and Ixabepilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive myelosuppressive effects.
What to do
Monitor blood counts frequently and adjust or delay doses according to neutrophil and platelet thresholds.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydroxyurea
Frequently asked questions
Can I take Hydroxyurea with Ixabepilone?
MediHelp rates the interaction as moderate. Hydroxyurea and Ixabepilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs suppress bone marrow. The combination may produce more severe neutropenia and thrombocytopenia.
How serious is the interaction between Hydroxyurea and Ixabepilone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts frequently and adjust or delay doses according to neutrophil and platelet thresholds.
What other medicines interact with Hydroxyurea?
MediHelp also lists interactions of Hydroxyurea with, for example, Didanosine, Adenovirus types 4 and 7 live, Axicabtagene ciloleucel. The full list is on the Hydroxyurea page.
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