Drug interactions
Ibandronate + Polysaccharide iron
Severity: Moderate
Ibandronate and Polysaccharide iron: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral iron can chelate ibandronate in the gut and lower its absorption, potentially reducing its efficacy.
What this interaction means in plain words
Ibandronate and Polysaccharide iron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Chelation of ibandronate by polyvalent iron cations in the GI tract reduces absorption.
What to do
Take oral ibandronate with plain water after fasting and delay the iron preparation for at least 60 minutes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Ibandronate and Polysaccharide iron, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Ibandronate
- Aluminum hydroxide + Ibandronate Moderate
- Calcium acetate + Ibandronate Moderate
- Calcium carbonate + Ibandronate Moderate
- Calcium chloride + Ibandronate Moderate
- Calcium citrate + Ibandronate Moderate
- Calcium gluconate + Ibandronate Moderate
Frequently asked questions
Can I take Ibandronate with Polysaccharide iron?
MediHelp rates the interaction as moderate. Ibandronate and Polysaccharide iron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron can chelate ibandronate in the gut and lower its absorption, potentially reducing its efficacy.
How serious is the interaction between Ibandronate and Polysaccharide iron?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take oral ibandronate with plain water after fasting and delay the iron preparation for at least 60 minutes.
What other medicines interact with Ibandronate?
MediHelp also lists interactions of Ibandronate with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Ibandronate page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
