Drug interactions
Ibuprofen + Methyl aminolevulinate
Severity: Minor
Ibuprofen and Methyl aminolevulinate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Methyl aminolevulinate is used topically with light for photodynamic therapy, and systemic photosensitizing drugs could intensify the skin reaction. Systemic exposure to the topical agent is minimal and ibuprofen has low phototoxic potential, so clinical significance is small.
What this interaction means in plain words
Ibuprofen and Methyl aminolevulinate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive phototoxicity at the illuminated skin site.
What to do
Counsel patients to protect treated skin from light after therapy and report severe local reactions.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ibuprofen
- Ibuprofen + Ketorolac Contraindicated
- Ibuprofen + Ketorolac intranasal Contraindicated
- Acemetacin + Ibuprofen Major
- Alteplase + Ibuprofen Major
- Amiloride + Ibuprofen Major
- Apixaban + Ibuprofen Major
Frequently asked questions
Can I take Ibuprofen with Methyl aminolevulinate?
MediHelp rates the interaction as minor. Ibuprofen and Methyl aminolevulinate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Methyl aminolevulinate is used topically with light for photodynamic therapy, and systemic photosensitizing drugs could intensify the skin reaction. Systemic exposure to the topical agent is minimal and ibuprofen has low phototoxic potential, so clinical significance is small.
How serious is the interaction between Ibuprofen and Methyl aminolevulinate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to protect treated skin from light after therapy and report severe local reactions.
What other medicines interact with Ibuprofen?
MediHelp also lists interactions of Ibuprofen with, for example, Ketorolac, Ketorolac intranasal, Acemetacin. The full list is on the Ibuprofen page.
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