Drug interactions
Ibuprofen + Reishi
Severity: Minor
Ibuprofen and Reishi: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reishi mushroom has been reported to have antiplatelet activity and may add to the bleeding tendency associated with ibuprofen. The evidence is limited and largely theoretical.
What this interaction means in plain words
Ibuprofen and Reishi have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive platelet inhibition; reishi's effect on platelet function is not firmly established.
What to do
Ask patients about herbal use and advise against combining if they have other bleeding risks. Monitor for bruising or bleeding if used together.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Ibuprofen and Reishi, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Ibuprofen
- Ibuprofen + Ketorolac Contraindicated
- Ibuprofen + Ketorolac intranasal Contraindicated
- Acemetacin + Ibuprofen Major
- Alteplase + Ibuprofen Major
- Amiloride + Ibuprofen Major
- Apixaban + Ibuprofen Major
Frequently asked questions
Can I take Ibuprofen with Reishi?
MediHelp rates the interaction as minor. Ibuprofen and Reishi have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reishi mushroom has been reported to have antiplatelet activity and may add to the bleeding tendency associated with ibuprofen. The evidence is limited and largely theoretical.
How serious is the interaction between Ibuprofen and Reishi?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and advise against combining if they have other bleeding risks. Monitor for bruising or bleeding if used together.
What other medicines interact with Ibuprofen?
MediHelp also lists interactions of Ibuprofen with, for example, Ketorolac, Ketorolac intranasal, Acemetacin. The full list is on the Ibuprofen page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
