Drug interactions
Ibuprofen / famotidine + Triamcinolone
Severity: Moderate
Ibuprofen / famotidine and Triamcinolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids combined with NSAIDs raise the risk of gastric irritation, ulceration and gastrointestinal bleeding. Famotidine may partly lower ulcer risk but does not remove it.
What this interaction means in plain words
Ibuprofen / famotidine and Triamcinolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive gastrointestinal mucosal injury from NSAID prostaglandin inhibition and corticosteroid effects on mucosal defense.
What to do
Use the lowest effective doses for the shortest time and consider a proton pump inhibitor in high-risk patients. Monitor for dyspepsia, melena and other GI bleeding signs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Triamcinolone
- Smallpox vaccine live + Triamcinolone Contraindicated
- Triamcinolone + Zoster vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Triamcinolone Major
- Aldesleukin + Triamcinolone Major
- Atazanavir + Triamcinolone Major
- Axicabtagene ciloleucel + Triamcinolone Major
Frequently asked questions
Can I take Ibuprofen / famotidine with Triamcinolone?
MediHelp rates the interaction as moderate. Ibuprofen / famotidine and Triamcinolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticosteroids combined with NSAIDs raise the risk of gastric irritation, ulceration and gastrointestinal bleeding. Famotidine may partly lower ulcer risk but does not remove it.
How serious is the interaction between Ibuprofen / famotidine and Triamcinolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses for the shortest time and consider a proton pump inhibitor in high-risk patients. Monitor for dyspepsia, melena and other GI bleeding signs.
What other medicines interact with Triamcinolone?
MediHelp also lists interactions of Triamcinolone with, for example, Smallpox vaccine live, Zoster vaccine live, Adenovirus types 4 and 7 live. The full list is on the Triamcinolone page.
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