Drug interactions
Icosapent + Naproxen
Severity: Minor
Icosapent and Naproxen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Icosapent ethyl may modestly prolong bleeding time and can add to the antiplatelet effect of naproxen. Bleeding events are generally minor.
What this interaction means in plain words
Icosapent and Naproxen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive mild inhibition of platelet aggregation.
What to do
Monitor periodically for bleeding, particularly in patients with other hemostatic risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Naproxen
- Ketorolac intranasal + Naproxen Contraindicated
- Ketorolac + Naproxen Contraindicated
- Aceclofenac + Naproxen Major
- Acemetacin + Naproxen Major
- Acetylsalicylic acid + Naproxen Major
- Alteplase + Naproxen Major
Frequently asked questions
Can I take Icosapent with Naproxen?
MediHelp rates the interaction as minor. Icosapent and Naproxen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Icosapent ethyl may modestly prolong bleeding time and can add to the antiplatelet effect of naproxen. Bleeding events are generally minor.
How serious is the interaction between Icosapent and Naproxen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor periodically for bleeding, particularly in patients with other hemostatic risk factors.
What other medicines interact with Naproxen?
MediHelp also lists interactions of Naproxen with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Naproxen page.
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