Drug interactions
Icosapent + Tolmetin
Severity: Minor
Icosapent and Tolmetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Icosapent ethyl may modestly prolong bleeding time and has been associated with increased bleeding in patients on other antithrombotic drugs. With an NSAID the risk may be slightly increased.
What this interaction means in plain words
Icosapent and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antiplatelet effects of EPA and NSAID COX inhibition.
What to do
Monitor periodically for bleeding signs, especially in patients with a history of gastrointestinal bleeding or on other antithrombotics.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Frequently asked questions
Can I take Icosapent with Tolmetin?
MediHelp rates the interaction as minor. Icosapent and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Icosapent ethyl may modestly prolong bleeding time and has been associated with increased bleeding in patients on other antithrombotic drugs. With an NSAID the risk may be slightly increased.
How serious is the interaction between Icosapent and Tolmetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor periodically for bleeding signs, especially in patients with a history of gastrointestinal bleeding or on other antithrombotics.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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