Drug interactions
Ifosfamide + Schisandra
Severity: Minor
Ifosfamide and Schisandra: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Schisandra constituents have shown CYP3A4 effects in laboratory and limited human studies, so they might alter ifosfamide metabolism. The direction and size of the effect in patients are not established.
What this interaction means in plain words
Ifosfamide and Schisandra have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible modulation of CYP3A4 by schisandra constituents; not clearly established clinically.
What to do
Advise patients to avoid herbal supplements such as schisandra during ifosfamide chemotherapy. Monitor response and toxicity if used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Contraindicated
- Ifosfamide + Measles mumps and rubella vaccine Contraindicated
- Ifosfamide + Measles mumps and rubella vaccine live Contraindicated
- Ifosfamide + Measles mumps rubella and varicella vaccine live Contraindicated
- Ifosfamide + Measles vaccine Contraindicated
- Ifosfamide + Rotavirus oral vaccine live Contraindicated
Frequently asked questions
Can I take Ifosfamide with Schisandra?
MediHelp rates the interaction as minor. Ifosfamide and Schisandra have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Schisandra constituents have shown CYP3A4 effects in laboratory and limited human studies, so they might alter ifosfamide metabolism. The direction and size of the effect in patients are not established.
How serious is the interaction between Ifosfamide and Schisandra?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid herbal supplements such as schisandra during ifosfamide chemotherapy. Monitor response and toxicity if used.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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