Drug interactions
Iloprost inhaled + Minoxidil
Severity: Moderate
Iloprost inhaled and Minoxidil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloprost is a prostacyclin analog with vasodilating activity, and minoxidil is a strong systemic vasodilator. Together they may increase the risk of hypotension, flushing and reflex tachycardia. Inhaled administration limits systemic exposure, so the effect is usually modest.
What this interaction means in plain words
Iloprost inhaled and Minoxidil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive vasodilation via prostacyclin receptor agonism and potassium channel opening.
What to do
Monitor blood pressure and symptoms of hypotension after starting iloprost. Reduce the minoxidil dose if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Iloprost inhaled and Minoxidil, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Minoxidil
Frequently asked questions
Can I take Iloprost inhaled with Minoxidil?
MediHelp rates the interaction as moderate. Iloprost inhaled and Minoxidil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloprost is a prostacyclin analog with vasodilating activity, and minoxidil is a strong systemic vasodilator. Together they may increase the risk of hypotension, flushing and reflex tachycardia. Inhaled administration limits systemic exposure, so the effect is usually modest.
How serious is the interaction between Iloprost inhaled and Minoxidil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and symptoms of hypotension after starting iloprost. Reduce the minoxidil dose if needed.
What other medicines interact with Minoxidil?
MediHelp also lists interactions of Minoxidil with, for example, Aldesleukin, Amifostine, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Minoxidil page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
