Drug interactions
Indacaterol inhaled + Nilotinib
Severity: Moderate
Indacaterol inhaled and Nilotinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indacaterol, a long-acting beta-agonist, may prolong the QT interval at high exposures, and nilotinib also prolongs QT. Combined use may modestly increase arrhythmia risk, particularly with hypokalemia.
What this interaction means in plain words
Indacaterol inhaled and Nilotinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QTc prolongation; beta-agonists can also lower serum potassium.
What to do
Monitor the ECG and serum potassium, and correct electrolyte disturbances. Use indacaterol at the labeled dose only.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nilotinib
- Amiodarone + Nilotinib Contraindicated
- Arsenic trioxide + Nilotinib Contraindicated
- Disopyramide + Nilotinib Contraindicated
- Dofetilide + Nilotinib Contraindicated
- Dronedarone + Nilotinib Contraindicated
- Droperidol + Nilotinib Contraindicated
Frequently asked questions
Can I take Indacaterol inhaled with Nilotinib?
MediHelp rates the interaction as moderate. Indacaterol inhaled and Nilotinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indacaterol, a long-acting beta-agonist, may prolong the QT interval at high exposures, and nilotinib also prolongs QT. Combined use may modestly increase arrhythmia risk, particularly with hypokalemia.
How serious is the interaction between Indacaterol inhaled and Nilotinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor the ECG and serum potassium, and correct electrolyte disturbances. Use indacaterol at the labeled dose only.
What other medicines interact with Nilotinib?
MediHelp also lists interactions of Nilotinib with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Nilotinib page.
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