Drug interactions
Indacaterol inhaled + Quinine
Severity: Moderate
Indacaterol inhaled and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indacaterol can prolong the QTc interval, mainly at higher systemic exposure, and quinine adds to this effect. The risk of ventricular arrhythmia is raised, especially with hypokalemia or other risk factors.
What this interaction means in plain words
Indacaterol inhaled and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation; beta-agonist effects may also lower potassium.
What to do
Check potassium and consider an ECG in patients with cardiac disease or other QT risk factors. Use the recommended indacaterol dose only.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Frequently asked questions
Can I take Indacaterol inhaled with Quinine?
MediHelp rates the interaction as moderate. Indacaterol inhaled and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indacaterol can prolong the QTc interval, mainly at higher systemic exposure, and quinine adds to this effect. The risk of ventricular arrhythmia is raised, especially with hypokalemia or other risk factors.
How serious is the interaction between Indacaterol inhaled and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and consider an ECG in patients with cardiac disease or other QT risk factors. Use the recommended indacaterol dose only.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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