Drug interactions
Indapamide + Meloxicam
Severity: Moderate
Indapamide and Meloxicam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs can reduce the antihypertensive and diuretic effect of indapamide. In dehydrated or older patients the combination can contribute to renal impairment.
What this interaction means in plain words
Indapamide and Meloxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indapamide belongs to Cardiovascular; Meloxicam belongs to Musculoskeletal.
Why it happens
Meloxicam inhibits renal prostaglandins, causing sodium retention and lowering renal perfusion.
What to do
Monitor blood pressure, renal function and electrolytes, and maintain hydration.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Meloxicam
- Ketorolac intranasal + Meloxicam Contraindicated
- Ketorolac + Meloxicam Contraindicated
- Aceclofenac + Meloxicam Major
- Acemetacin + Meloxicam Major
- Acetylsalicylic acid + Meloxicam Major
- Alteplase + Meloxicam Major
Other interactions of Indapamide
Frequently asked questions
Can I take Indapamide with Meloxicam?
MediHelp rates the interaction as moderate. Indapamide and Meloxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. NSAIDs can reduce the antihypertensive and diuretic effect of indapamide. In dehydrated or older patients the combination can contribute to renal impairment.
How serious is the interaction between Indapamide and Meloxicam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, renal function and electrolytes, and maintain hydration.
What other medicines interact with Meloxicam?
MediHelp also lists interactions of Meloxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meloxicam page.
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