Drug interactions
Indapamide + Telavancin
Severity: Moderate
Indapamide and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indapamide can prolong the QT interval and cause hypokalemia and hypomagnesemia, which further increase arrhythmia risk. Adding telavancin may compound the risk of torsades de pointes.
What this interaction means in plain words
Indapamide and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indapamide belongs to Cardiovascular; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QTc prolongation, with indapamide-induced electrolyte depletion as an added proarrhythmic factor.
What to do
Monitor serum potassium and magnesium and replace as needed. Obtain an ECG if other risk factors for QT prolongation are present.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Indapamide
Frequently asked questions
Can I take Indapamide with Telavancin?
MediHelp rates the interaction as moderate. Indapamide and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indapamide can prolong the QT interval and cause hypokalemia and hypomagnesemia, which further increase arrhythmia risk. Adding telavancin may compound the risk of torsades de pointes.
How serious is the interaction between Indapamide and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium and replace as needed. Obtain an ECG if other risk factors for QT prolongation are present.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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