Drug interactions
Influenza virus vaccine quadrivalent adjuvanted + Tocilizumab
Severity: Minor
Influenza virus vaccine quadrivalent adjuvanted and Tocilizumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tocilizumab may modestly reduce the antibody response to inactivated influenza vaccine, though protective responses are generally still achieved. The vaccine is non-live and should not be withheld.
What this interaction means in plain words
Influenza virus vaccine quadrivalent adjuvanted and Tocilizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
IL-6 blockade may modestly blunt humoral vaccine response.
What to do
Give the inactivated influenza vaccine as recommended without interrupting tocilizumab.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Influenza virus vaccine quadrivalent adjuvanted and Tocilizumab, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Tocilizumab
- Bcg vaccine live + Tocilizumab Contraindicated
- Measles mumps and rubella vaccine live + Tocilizumab Contraindicated
- Measles mumps rubella and varicella vaccine live + Tocilizumab Contraindicated
- Measles vaccine + Tocilizumab Contraindicated
- Rubella vaccine + Tocilizumab Contraindicated
- Smallpox vaccine live + Tocilizumab Contraindicated
Frequently asked questions
Can I take Influenza virus vaccine quadrivalent adjuvanted with Tocilizumab?
MediHelp rates the interaction as minor. Influenza virus vaccine quadrivalent adjuvanted and Tocilizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tocilizumab may modestly reduce the antibody response to inactivated influenza vaccine, though protective responses are generally still achieved. The vaccine is non-live and should not be withheld.
How serious is the interaction between Influenza virus vaccine quadrivalent adjuvanted and Tocilizumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the inactivated influenza vaccine as recommended without interrupting tocilizumab.
What other medicines interact with Tocilizumab?
MediHelp also lists interactions of Tocilizumab with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Tocilizumab page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
