Drug interactions
Influenza virus vaccine quadrivalent + Tocilizumab
Severity: Minor
Influenza virus vaccine quadrivalent and Tocilizumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inactivated influenza vaccine can be given with tocilizumab. Antibody responses are generally adequate, though somewhat lower in some patients. Annual vaccination remains advisable.
What this interaction means in plain words
Influenza virus vaccine quadrivalent and Tocilizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Pharmacodynamic: IL-6 receptor blockade may modestly attenuate vaccine response.
What to do
Give annual inactivated influenza vaccine as recommended. No tocilizumab adjustment is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tocilizumab
- Bcg vaccine live + Tocilizumab Contraindicated
- Measles mumps and rubella vaccine live + Tocilizumab Contraindicated
- Measles mumps rubella and varicella vaccine live + Tocilizumab Contraindicated
- Measles vaccine + Tocilizumab Contraindicated
- Rubella vaccine + Tocilizumab Contraindicated
- Smallpox vaccine live + Tocilizumab Contraindicated
Frequently asked questions
Can I take Influenza virus vaccine quadrivalent with Tocilizumab?
MediHelp rates the interaction as minor. Influenza virus vaccine quadrivalent and Tocilizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inactivated influenza vaccine can be given with tocilizumab. Antibody responses are generally adequate, though somewhat lower in some patients. Annual vaccination remains advisable.
How serious is the interaction between Influenza virus vaccine quadrivalent and Tocilizumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give annual inactivated influenza vaccine as recommended. No tocilizumab adjustment is needed.
What other medicines interact with Tocilizumab?
MediHelp also lists interactions of Tocilizumab with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Tocilizumab page.
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