Drug interactions
Insulin aspart + Moexipril
Severity: Moderate
Insulin aspart and Moexipril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors may increase insulin sensitivity and enhance the glucose-lowering effect of insulin. This can lead to hypoglycemia, particularly after starting the ACE inhibitor.
What this interaction means in plain words
Insulin aspart and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin aspart belongs to Endocrine; Moexipril belongs to Cardiovascular.
Why it happens
Pharmacodynamic synergism: ACE inhibition improves insulin sensitivity and glucose uptake.
What to do
Monitor blood glucose more often when starting moexipril and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Other interactions of Insulin aspart
Frequently asked questions
Can I take Insulin aspart with Moexipril?
MediHelp rates the interaction as moderate. Insulin aspart and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. ACE inhibitors may increase insulin sensitivity and enhance the glucose-lowering effect of insulin. This can lead to hypoglycemia, particularly after starting the ACE inhibitor.
How serious is the interaction between Insulin aspart and Moexipril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more often when starting moexipril and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
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