Drug interactions
Insulin aspart + Valsartan
Severity: Moderate
Insulin aspart and Valsartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may enhance insulin sensitivity and increase the glucose-lowering effect of insulin. This can lead to hypoglycemia, especially after starting valsartan or when doses are increased.
What this interaction means in plain words
Insulin aspart and Valsartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin aspart belongs to Endocrine; Valsartan belongs to Cardiovascular.
Why it happens
Improved insulin sensitivity with angiotensin receptor blockade produces additive glucose lowering.
What to do
Monitor blood glucose more frequently when valsartan is started or changed, and reduce insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Insulin aspart and Valsartan, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Valsartan
- Aliskiren + Valsartan Contraindicated
- Sparsentan + Valsartan Contraindicated
- Aldesleukin + Valsartan Major
- Amifostine + Valsartan Major
- Amiloride + Valsartan Major
- Amlodipine-benazepril + Valsartan Major
Other interactions of Insulin aspart
Frequently asked questions
Can I take Insulin aspart with Valsartan?
MediHelp rates the interaction as moderate. Insulin aspart and Valsartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Angiotensin receptor blockers may enhance insulin sensitivity and increase the glucose-lowering effect of insulin. This can lead to hypoglycemia, especially after starting valsartan or when doses are increased.
How serious is the interaction between Insulin aspart and Valsartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when valsartan is started or changed, and reduce insulin dose if hypoglycemia occurs.
What other medicines interact with Valsartan?
MediHelp also lists interactions of Valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Valsartan page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
