Drug interactions
Insulin degludec + Telmisartan-amlodipine
Severity: Minor
Insulin degludec and Telmisartan-amlodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may modestly improve insulin sensitivity, so patients on insulin can experience more frequent or more pronounced hypoglycemia. The effect is usually small and variable.
What this interaction means in plain words
Insulin degludec and Telmisartan-amlodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Insulin degludec belongs to Endocrine; Telmisartan-amlodipine belongs to Cardiovascular.
Why it happens
Probable improvement of insulin sensitivity by angiotensin II receptor blockade; the mechanism is not fully established.
What to do
Monitor blood glucose more frequently when telmisartan is started or stopped and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Insulin degludec and Telmisartan-amlodipine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Other interactions of Insulin degludec
Frequently asked questions
Can I take Insulin degludec with Telmisartan-amlodipine?
MediHelp rates the interaction as minor. Insulin degludec and Telmisartan-amlodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may modestly improve insulin sensitivity, so patients on insulin can experience more frequent or more pronounced hypoglycemia. The effect is usually small and variable.
How serious is the interaction between Insulin degludec and Telmisartan-amlodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when telmisartan is started or stopped and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
