Drug interactions
Insulin degludec / insulin aspart + Moexipril
Severity: Moderate
Insulin degludec / insulin aspart and Moexipril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors can increase insulin sensitivity and enhance the glucose-lowering effect of insulin. This may lead to hypoglycemia, particularly shortly after the ACE inhibitor is started.
What this interaction means in plain words
Insulin degludec / insulin aspart and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Improved insulin sensitivity with ACE inhibition adds to exogenous insulin effect.
What to do
Monitor blood glucose more frequently when starting or adjusting the ACE inhibitor and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Frequently asked questions
Can I take Insulin degludec / insulin aspart with Moexipril?
MediHelp rates the interaction as moderate. Insulin degludec / insulin aspart and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. ACE inhibitors can increase insulin sensitivity and enhance the glucose-lowering effect of insulin. This may lead to hypoglycemia, particularly shortly after the ACE inhibitor is started.
How serious is the interaction between Insulin degludec / insulin aspart and Moexipril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when starting or adjusting the ACE inhibitor and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
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