Drug interactions
Insulin degludec-liraglutide + Levonorgestrel intrauterine
Severity: Minor
Insulin degludec-liraglutide and Levonorgestrel intrauterine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Intrauterine levonorgestrel has low systemic exposure, so its effect on glucose tolerance is minimal. A clinically meaningful interaction is unlikely.
What this interaction means in plain words
Insulin degludec-liraglutide and Levonorgestrel intrauterine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical progestin-related impairment of glucose tolerance, with minimal systemic exposure.
What to do
No dose change is generally needed. Continue routine glucose monitoring.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Frequently asked questions
Can I take Insulin degludec-liraglutide with Levonorgestrel intrauterine?
MediHelp rates the interaction as minor. Insulin degludec-liraglutide and Levonorgestrel intrauterine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Intrauterine levonorgestrel has low systemic exposure, so its effect on glucose tolerance is minimal. A clinically meaningful interaction is unlikely.
How serious is the interaction between Insulin degludec-liraglutide and Levonorgestrel intrauterine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is generally needed. Continue routine glucose monitoring.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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