Drug interactions
Insulin degludec-liraglutide + Magnesium salicylate
Severity: Moderate
Insulin degludec-liraglutide and Magnesium salicylate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High doses of salicylates can lower blood glucose and enhance the effect of insulin. Hypoglycemia is more likely when the combination is used regularly at analgesic or anti-inflammatory doses.
What this interaction means in plain words
Insulin degludec-liraglutide and Magnesium salicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Salicylates increase insulin secretion and peripheral glucose utilization and reduce hepatic glucose output, adding to the insulin effect.
What to do
Monitor blood glucose more often when salicylates are used at high doses and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin degludec-liraglutide
Frequently asked questions
Can I take Insulin degludec-liraglutide with Magnesium salicylate?
MediHelp rates the interaction as moderate. Insulin degludec-liraglutide and Magnesium salicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. High doses of salicylates can lower blood glucose and enhance the effect of insulin. Hypoglycemia is more likely when the combination is used regularly at analgesic or anti-inflammatory doses.
How serious is the interaction between Insulin degludec-liraglutide and Magnesium salicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more often when salicylates are used at high doses and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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